Research Articles
The Molecular Acrobat: How a Tiny Enzyme Crafts a Life-Saving Antibiotic
Discover how the HppE enzyme creates the critical antibiotic fosfomycin through quantum mechanical precision and radical chemistry.
The Diradical Dance: How a Two-Radical Tango Builds Nature's Quantum Lego
Discover how enzymes harness radical chemistry with surgical precision to build essential cofactors like tryptophan tryptophylquinone (TTQ) through controlled diradical intermediates.
The Enzyme That Defied Chemistry's Rules: Unlocking Lasalocid's Molecular Magic
Discover how the lasalocid biosynthetic pathway challenges Baldwin's rules through enzymatic catalysis of disfavored ring closures.
Hidden Choreography: How a Bacterial Enzyme's Dance Holds Keys to New Antibiotics
Exploring the molecular mechanisms of A. baumannii's ATP phosphoribosyltransferase and its potential as an antibiotic target